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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARAF
All Species:
4.55
Human Site:
T223
Identified Species:
8.33
UniProt:
P10398
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10398
NP_001645.1
606
67585
T223
P
N
V
H
M
V
S
T
T
A
P
M
D
S
N
Chimpanzee
Pan troglodytes
XP_001155232
648
73032
N262
Q
R
S
T
S
T
P
N
V
H
M
V
S
T
T
Rhesus Macaque
Macaca mulatta
XP_001094928
606
67485
T223
P
N
V
H
M
V
S
T
T
A
P
M
D
S
N
Dog
Lupus familis
XP_548976
597
66626
V214
R
S
T
S
T
P
N
V
H
M
V
S
T
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P04627
604
67563
V221
S
T
P
N
V
H
M
V
S
T
T
A
P
M
D
Rat
Rattus norvegicus
P14056
604
67533
V221
S
T
P
N
V
H
M
V
S
T
T
A
P
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516512
799
90020
P402
R
K
Y
Q
S
R
T
P
S
P
L
L
H
S
V
Chicken
Gallus gallus
P05625
647
73106
N262
Q
R
S
T
S
T
P
N
V
H
M
V
S
T
T
Frog
Xenopus laevis
P09560
638
71941
Q253
E
C
S
L
S
Q
R
Q
R
S
T
S
T
P
N
Zebra Danio
Brachydanio rerio
NP_991306
608
68644
M225
T
S
T
P
N
V
H
M
V
S
T
L
E
P
G
Tiger Blowfish
Takifugu rubipres
NP_001033077
573
64648
P197
P
A
F
H
F
P
M
P
G
G
D
G
Q
S
L
Fruit Fly
Dros. melanogaster
P11346
782
88616
D385
P
P
R
I
S
Q
D
D
R
S
N
S
A
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
C394
S
N
S
P
S
S
T
C
S
S
P
P
G
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.1
97
92.7
N.A.
95.2
95.5
N.A.
47.6
58.1
57.8
67.4
63.5
34.5
N.A.
32.8
N.A.
Protein Similarity:
100
70.8
97.6
94
N.A.
97
97
N.A.
57.7
71.2
70.6
77.8
74.2
48.8
N.A.
48
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
6.6
0
6.6
6.6
20
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
100
20
N.A.
26.6
26.6
N.A.
26.6
13.3
13.3
33.3
20
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
16
0
16
8
0
8
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
0
0
8
0
16
0
16
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
0
8
8
8
8
% G
% His:
0
0
0
24
0
16
8
0
8
16
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
8
16
0
0
16
% L
% Met:
0
0
0
0
16
0
24
8
0
8
16
16
0
16
0
% M
% Asn:
0
24
0
16
8
0
8
16
0
0
8
0
0
0
31
% N
% Pro:
31
8
16
16
0
16
16
16
0
8
24
8
16
24
0
% P
% Gln:
16
0
0
8
0
16
0
8
0
0
0
0
8
0
0
% Q
% Arg:
16
16
8
0
0
8
8
0
16
0
0
0
0
0
0
% R
% Ser:
24
16
31
8
47
8
16
0
31
31
0
24
16
31
0
% S
% Thr:
8
16
16
16
8
16
16
16
16
16
31
0
16
24
16
% T
% Val:
0
0
16
0
16
24
0
24
24
0
8
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _